Study for the Medical Council of Canada Qualifying Examination (MCCQE) I. Engage with flashcards and multiple-choice questions with detailed feedback. Prepare confidently!

Multiple Choice

In a patient with CKD and potassium 6.0 mEq/L with tall peaked T waves on ECG, what is the immediate management?

The first priority in hyperkalemia with ECG changes is to protect the heart while you begin lowering the potassium. Calcium gluconate stabilizes the cardiac cell membranes, raising the threshold for depolarization so the myocardium is less likely to develop dangerous rhythm disturbances. This stabilization is temporary but crucial and does not lower potassium itself, so it buys you time. After the heart is stabilized, shift potassium into cells by giving insulin with glucose; a beta-agonist such as albuterol can further promote intracellular potassium uptake. IV bicarbonate can be helpful if there is metabolic acidosis, but it is not sufficient on its own to rapidly reduce potassium. Giving potassium supplements would worsen the situation, and hemodialysis, while definitive for patients with CKD, is not the immediate step when you can safely initiate calcium stabilization followed by shifting therapy.

The first priority in hyperkalemia with ECG changes is to protect the heart while you begin lowering the potassium. Calcium gluconate stabilizes the cardiac cell membranes, raising the threshold for depolarization so the myocardium is less likely to develop dangerous rhythm disturbances. This stabilization is temporary but crucial and does not lower potassium itself, so it buys you time. After the heart is stabilized, shift potassium into cells by giving insulin with glucose; a beta-agonist such as albuterol can further promote intracellular potassium uptake. IV bicarbonate can be helpful if there is metabolic acidosis, but it is not sufficient on its own to rapidly reduce potassium. Giving potassium supplements would worsen the situation, and hemodialysis, while definitive for patients with CKD, is not the immediate step when you can safely initiate calcium stabilization followed by shifting therapy.