Tamoxifen has what effect on bone?

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Multiple Choice

Tamoxifen has what effect on bone?

Tamoxifen is a selective estrogen receptor modulator, so its effects vary by tissue. In bone, it acts like estrogen, helping to inhibit osteoclast activity and reduce bone resorption, which maintains or improves bone mineral density. That is why it is described as osteoprotective. In contrast, it does not lower the risk of DVT and can raise the risk of endometrial-related issues due to its estrogenic action on the uterus, which is why those statements aren’t correct for bone.

Tamoxifen is a selective estrogen receptor modulator, so its effects vary by tissue. In bone, it acts like estrogen, helping to inhibit osteoclast activity and reduce bone resorption, which maintains or improves bone mineral density. That is why it is described as osteoprotective. In contrast, it does not lower the risk of DVT and can raise the risk of endometrial-related issues due to its estrogenic action on the uterus, which is why those statements aren’t correct for bone.

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